Biochemical and haematological enhancement activities of aqueous and methanol leaves, stem and roots extracts of Chasmanthera dependens (Hochst) and Dictyandra arborescens (Welw.)

Abstract Background Africa is blessed with rich floral biodiversity which are harnessed as herbal medicines and remedies for several ailments. Since there has been evidence of organ toxicity following prolonged ingestion medicinal plant concotions, this study investigated the biochemical hematological enhancement activities aqueous methanolic leaves, stem roots extracts Chasmanthera dependens (Hochst) Dictyandra arborescens (Welw) in adult male albino rats. Results Leaves, D. , well leaves C. did not record any mice mortality even at 5000 mg/kg b.wt but both medium recorded death 2900 b. wt b.wt. Ingestion by rats over a 14-day period increased ( p < 0.05) body weights experimental animals treated groups. The relative that received differ significantly from those standard normal control. Administration revealed significant increase haematological parameters (PCV, Hb, RBCs, WBCs, MCH, Neutrophils, Lymphocytes MCHC) 200 −1 weight. For parameters, levels ALT, AST, ALP, total protein, albumin were elevated administration extracts. Conclusion These these exhibit chronic on animals, suggesting no harmful effects their use, continuous use ethno-medicine therefore justified.